In this research work, we have demonstrated the application of Mask-RCNN (Regional Convolutional Neural Network), a deep-learning algorithm for computer vision and specifically object detection, to semiconductor defect inspection domain. Stochastic defect detection and classification during semiconductor manufacturing has grown to be a challenging task as we continuously shrink circuit pattern dimensions (e.g., for pitches less than 32 nm). Defect inspection and analysis by state-of-the-art optical and e-beam inspection tools is generally driven by some rule-based techniques, which in turn often causes to misclassification and thereby necessitating human expert intervention. In this work, we have revisited and extended our previous deep learning-based defect classification and detection method towards improved defect instance segmentation in SEM images with precise extent of defect as well as generating a mask for each defect category/instance. This also enables to extract and calibrate each segmented mask and quantify the pixels that make up each mask, which in turn enables us to count each categorical defect instances as well as to calculate the surface area in terms of pixels. We are aiming at detecting and segmenting different types of inter-class stochastic defect patterns such as bridge, break, and line collapse as well as to differentiate accurately between intra-class multi-categorical defect bridge scenarios (as thin/single/multi-line/horizontal/non-horizontal) for aggressive pitches as well as thin resists (High NA applications). Our proposed approach demonstrates its effectiveness both quantitatively and qualitatively.

Inferring knowledge from clinical trials using knowledge graph embedding is an emerging area. However, customizing graph embeddings for different use cases remains a significant challenge. We propose custom2vec, an algorithmic framework to customize graph embeddings by incorporating user preferences in training the embeddings. It captures user preferences by adding custom nodes and links derived from manually vetted results of a separate information retrieval method. We propose a joint learning objective to preserve the original network structure while incorporating the user's custom annotations. We hypothesize that the custom training improves user-expected predictions, for example, in link prediction tasks. We demonstrate the effectiveness of custom2vec for clinical trials related to non-small cell lung cancer (NSCLC) with two customization scenarios: recommending immuno-oncology trials evaluating PD-1 inhibitors and exploring similar trials that compare new therapies with a standard of care. The results show that custom2vec training achieves better performance than the conventional training methods. Our approach is a novel way to customize knowledge graph embeddings and enable more accurate recommendations and predictions.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

The concept of walkable urban development has gained increased attention due to its public health, economic, and environmental sustainability benefits. Unfortunately, land zoning and historic under-investment have resulted in spatial inequality in walkability and social inequality among residents. We tackle the problem of Walkability Optimization through the lens of combinatorial optimization. The task is to select locations in which additional amenities (e.g., grocery stores, schools, restaurants) can be allocated to improve resident access via walking while taking into account existing amenities and providing multiple options (e.g., for restaurants). To this end, we derive Mixed-Integer Linear Programming (MILP) and Constraint Programming (CP) models. Moreover, we show that the problem's objective function is submodular in special cases, which motivates an efficient greedy heuristic. We conduct a case study on 31 underserved neighborhoods in the City of Toronto, Canada. MILP finds the best solutions in most scenarios but does not scale well with network size. The greedy algorithm scales well and finds near-optimal solutions. Our empirical evaluation shows that neighbourhoods with low walkability have a great potential for transformation into pedestrian-friendly neighbourhoods by strategically placing new amenities. Allocating 3 additional grocery stores, schools, and restaurants can improve the "WalkScore" by more than 50 points (on a scale of 100) for 4 neighbourhoods and reduce the walking distances to amenities for 75% of all residential locations to 10 minutes for all amenity types. Our code and paper appendix are available at https://github.com/khalil-research/walkability.

One of the main challenges in electroencephalogram (EEG) based brain-computer interface (BCI) systems is learning the subject/session invariant features to classify cognitive activities within an end-to-end discriminative setting. We propose a novel end-to-end machine learning pipeline, EEG-NeXt, which facilitates transfer learning by: i) aligning the EEG trials from different subjects in the Euclidean-space, ii) tailoring the techniques of deep learning for the scalograms of EEG signals to capture better frequency localization for low-frequency, longer-duration events, and iii) utilizing pretrained ConvNeXt (a modernized ResNet architecture which supersedes state-of-the-art (SOTA) image classification models) as the backbone network via adaptive finetuning. On publicly available datasets (Physionet Sleep Cassette and BNCI2014001) we benchmark our method against SOTA via cross-subject validation and demonstrate improved accuracy in cognitive activity classification along with better generalizability across cohorts.

Graph neural networks (GNNs) are susceptible to privacy inference attacks (PIAs), given their ability to learn joint representation from features and edges among nodes in graph data. To prevent privacy leakages in GNNs, we propose a novel heterogeneous randomized response (HeteroRR) mechanism to protect nodes' features and edges against PIAs under differential privacy (DP) guarantees without an undue cost of data and model utility in training GNNs. Our idea is to balance the importance and sensitivity of nodes' features and edges in redistributing the privacy budgets since some features and edges are more sensitive or important to the model utility than others. As a result, we derive significantly better randomization probabilities and tighter error bounds at both levels of nodes' features and edges departing from existing approaches, thus enabling us to maintain high data utility for training GNNs. An extensive theoretical and empirical analysis using benchmark datasets shows that HeteroRR significantly outperforms various baselines in terms of model utility under rigorous privacy protection for both nodes' features and edges. That enables us to defend PIAs in DP-preserving GNNs effectively.

National Health and Nutritional Status Survey (NHANSS) is conducted annually by the Ministry of Health in Negara Brunei Darussalam to assess the population health and nutritional patterns and characteristics. The main aim of this study was to discover meaningful patterns (groups) from the obese sample of NHANSS data by applying data reduction and interpretation techniques. The mixed nature of the variables (qualitative and quantitative) in the data set added novelty to the study. Accordingly, the Categorical Principal Component (CATPCA) technique was chosen to interpret the meaningful results. The relationships between obesity and the lifestyle factors like demography, socioeconomic status, physical activity, dietary behavior, history of blood pressure, diabetes, etc., were determined based on the principal components generated by CATPCA. The results were validated with the help of the split method technique to counter verify the authenticity of the generated groups. Based on the analysis and results, two subgroups were found in the data set, and the salient features of these subgroups have been reported. These results can be proposed for the betterment of the healthcare industry.

The Abstraction and Reasoning Corpus (ARC) aims at benchmarking the performance of general artificial intelligence algorithms. The ARC's focus on broad generalization and few-shot learning has made it difficult to solve using pure machine learning. A more promising approach has been to perform program synthesis within an appropriately designed Domain Specific Language (DSL). However, these too have seen limited success. We propose Abstract Reasoning with Graph Abstractions (ARGA), a new object-centric framework that first represents images using graphs and then performs a search for a correct program in a DSL that is based on the abstracted graph space. The complexity of this combinatorial search is tamed through the use of constraint acquisition, state hashing, and Tabu search. An extensive set of experiments demonstrates the promise of ARGA in tackling some of the complicated object-centric tasks of the ARC rather efficiently, producing programs that are correct and easy to understand.

目标：探索深度学习算法进一步简化和优化尿道板（UP）质量评估的能力，使用板客观评分工具（POST），旨在提高Hypospadias修复中提高评估的客观性和可重复性。方法：五个关键的邮政地标是由专家在691图像数据集中的专家标记，该数据集接受了原发性杂质修复的青春期前男孩。然后，该数据集用于开发和验证基于深度学习的地标检测模型。提出的框架始于瞥见和检测，其中输入图像是使用预测的边界框裁剪的。接下来，使用深层卷积神经网络（CNN）体系结构来预测五个邮政标记的坐标。然后，这些预测的地标用于评估远端催化性远端的质量。结果：所提出的模型准确地定位了gan区域，平均平均精度（地图）为99.5％，总体灵敏度为99.1％。在预测地标的坐标时，达到了0.07152的归一化平均误差（NME），平均平方误差（MSE）为0.001，在0.1 nme的阈值下为20.2％的故障率。结论：此深度学习应用程序在使用邮政评估质量时表现出鲁棒性和高精度。使用国际多中心基于图像的数据库进行进一步评估。外部验证可以使深度学习算法受益，并导致更好的评估，决策和对手术结果的预测。

最近的工作表明，通过将RL任务转换为监督学习任务，通过有条件的政策来解决离线加强学习（RL）可以产生有希望的结果。决策变压器（DT）结合了条件政策方法和变压器体系结构，以显示针对多个基准测试的竞争性能。但是，DT缺乏缝线能力 - 离线RL的关键能力之一，它从亚最佳轨迹中学习了最佳策略。当离线数据集仅包含亚最佳轨迹时，问题就变得很重要。另一方面，基于动态编程（例如Q学习）的常规RL方法不会遇到相同的问题；但是，他们患有不稳定的学习行为，尤其是当它在非政策学习环境中采用功能近似时。在本文中，我们提出了通过利用动态编程（Q-Learning）的好处来解决DT的缺点的Q学习决策者（QDT）。 QDT利用动态编程（Q-学习）结果来重新标记培训数据中的返回。然后，我们使用重新标记的数据训练DT。我们的方法有效利用了这两种方法的好处，并弥补了彼此的缺点，以取得更好的绩效。我们在简单的环境中演示了DT的问题和QDT的优势。我们还在更复杂的D4RL基准测试中评估了QDT，显示出良好的性能增长。